Examine EndoDraft: Semmelweis University Surgical Planning Software for Endovascular Procedures

Examine EndoDraft: Semmelweis University Surgical Planning Software for Endovascular Procedures

Advancements in medical technology continually reshape how vascular surgeons and interventional radiologists approach complex anatomical challenges. Among the most significant developments in recent years is the creation of specialized tools that improve precision and safety in the operating room. At the forefront of this innovation in Hungary, Semmelweis University has introduced a sophisticated solution designed specifically for the vascular specialty. This initiative demonstrates how academic institutions can develop practical, high-impact tools that directly address clinical needs.

Endovascular procedures, particularly those involving stent grafts for complex abdominal aortic aneurysms, require meticulous preparation. Because surgeons operate without a direct line of sight to the surgical site, they rely entirely on imaging devices. To mitigate the risks associated with this blind intervention, a new surgical planning software has been developed to simulate these operations in advance. This article examines the capabilities, development, and clinical implications of this software, highlighting its value for both active practitioners and medical students.

The Growing Need for Advanced Endovascular Planning

An aneurysm is a localized dilation of a blood vessel, and when it occurs in the abdominal section of the aorta—the body’s main artery—it presents a severe health risk. If an abdominal aortic aneurysm reaches an average diameter of 5.5 centimeters, the wall of the blood vessel becomes dangerously thin, and surgery becomes the only viable option to prevent a life-threatening rupture.

While traditional open surgery is highly invasive, the medical community increasingly favors minimally invasive endovascular procedures. In these operations, a stent graft—a flexible, biocompatible tube reinforced with a metallic mesh—is inserted via the femoral artery and navigated to the aneurysmal segment. Once deployed, the stent graft relieves the pressure on the weakened vessel wall.

Despite being less demanding for the patient regarding recovery time, endovascular procedures are highly complex from a surgical standpoint. The shape, size, and location of aneurysms vary drastically from patient to patient. Furthermore, the surgeon must rely solely on fluoroscopy and angiography to visualize the deployment. A minor miscalculation in stent graft sizing or placement can lead to endoleaks, where blood continues to flow into the aneurysm sac, or worse, occlusion of critical branching arteries such as the renal or mesenteric arteries. This clinical reality underscores the necessity for robust surgical planning software.

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How EndoDraft Addresses Complex Aortic Aneurysms

Developed at the Városmajor Heart and Vascular Center, EndoDraft was created to provide specialists with a reliable platform for preoperative planning. The software was initially designed specifically for complex abdominal aortic aneurysm stent graft procedures. It allows surgeons to tailor their surgical approach to the patient’s specific anatomy before the patient ever enters the operating room.

In emergency or acute settings, physicians sometimes encounter anatomies that cannot be treated with standard, off-the-shelf stent grafts. In these cases, they must modify the device intraoperatively—a process known as Physician-Modified Endograft (PMEG). Modifying a stent graft by hand in the operating room introduces a significant margin for error. EndoDraft mitigates this risk by calculating exactly where holes, known as fenestrations, must be made in the graft material to align with the patient’s branching vessels.

By utilizing this surgical planning software, the medical team can determine the exact size, placement, and type of stent graft required. The system calculates fenestration locations with millimeter accuracy, ensuring that the modified device will perfectly match the patient’s vascular anatomy once deployed.

Key Features of the EndoDraft Surgical Planning Software

EndoDraft stands out in the medical software landscape due to several unique features that are typically reserved for expensive, proprietary systems. Recognized as an intellectual creation by the University Innovation Committee, the software has undergone rigorous clinical validation, including a retrospective clinical trial published in the Journal of Endovascular Therapy.

3D Spatial Simulation and CT Integration

While the original version of the software utilized a 2D simulation module, the recently updated version introduces a complex 3D spatial planning module. Users can upload a patient’s standard DICOM CT scan directly into the software. The program then automatically segments the aorta and generates a fully manipulable 3D model. This allows surgeons to rotate, zoom, and inspect the aneurysm from any angle, facilitating a comprehensive understanding of the spatial relationships between the aneurysm and branching vessels. The latest module is capable of modeling virtually any type of endovascular procedure, making it highly versatile.

Strut Interference Analysis and Precision Fenestration

One of the most innovative aspects of EndoDraft is its ability to visualize the precise structure of the stent graft’s metallic mesh (struts) during the planning phase. When planning fenestrations, it is critical that the created holes do not collide with the metal frame of the device, as this could compromise the structural integrity of the stent or block the target vessel. EndoDraft highlights these potential collisions before the surgery takes place, allowing the planner to adjust the fenestration layout accordingly.

Furthermore, the software can generate a precision printing template using laser foil. This template acts as a physical guide that can be placed over the stent graft, enabling the physician to create the fenestrations with absolute accuracy during the PMEG process.

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3D Printing Compatibility

Beyond digital simulation, EndoDraft supports the export of patient-specific spatial anatomical models for 3D printing. This feature is particularly valuable for educational purposes and complex case reviews. By holding a physical 3D printed model of the patient’s aorta, surgical teams can better visualize the approach needed and practice the deployment of the modified stent graft in a tactile environment.

Educational Purposes and Research Applications in Hungary

The impact of EndoDraft extends far beyond the operating rooms of the Városmajor Heart and Vascular Center. Because it is available as a free download for educational and research purposes, it represents a significant resource for the global medical community, including institutions across Hungary. Previously, the advanced features offered by EndoDraft—such as strut interference analysis and 3D simulation—were only accessible through costly, specialized commercial software licenses. By removing this financial barrier, Semmelweis University has democratized access to high-end surgical planning tools.

In an academic setting, the software serves as an unparalleled teaching aid. Instructors can load a de-identified patient CT scan into the program and use the 3D visualization tools to demonstrate to students exactly how a stent graft is positioned and fitted within the anatomy. The software includes an internal, endoscopic camera view that allows users to see the planned fenestrations from inside the graft model. This visual perspective helps medical students and resident trainees grasp the spatial complexities of endovascular procedures much faster than traditional 2D imaging allows.

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Bridging Engineering and Medicine at Semmelweis University

The development of EndoDraft is a prime example of the value of interdisciplinary collaboration in medical technology. The software was developed by Bendegúz Juhos, a certified electrical engineer and PhD student at the Department of Interventional Radiology. Working under the supervision of Dr. Csaba Csobay-Novák, Juhos applied engineering principles to solve a distinct clinical problem.

Bringing an engineer into a medical research group focusing on aortic diseases provided a fresh perspective on the challenges of endovascular procedures. Juhos was able to translate the clinical requirements of vascular surgeons—such as the need for millimeter accuracy and strut collision avoidance—into functional algorithms and user-friendly software interfaces. This synergy between the technical and medical fields is exactly what drives forward the standard of care in modern healthcare. It highlights how PhD programs at leading institutions can yield tangible products that benefit both current clinical practice and future medical education.

The Future of Free Surgical Planning Tools

The trajectory of EndoDraft points toward a broader shift in how medical software is developed and distributed. As the complexity of endovascular procedures increases with the introduction of branched and fenestrated stent grafts, the demand for precise planning tools will only grow. The fact that a comprehensive, 3D-capable surgical planning software is now available free of charge sets a new precedent in the industry.

For researchers, the software provides a platform for conducting retrospective clinical trials and analyzing surgical outcomes without the confounding variable of inconsistent planning methodologies. For clinicians, it offers a reliable, cost-effective way to prepare for high-stakes interventions. As more users download and utilize the software, the potential for community-driven improvements and feature expansions increases, further solidifying its role in the medical landscape.

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